After Carl Wieselsberger had studied and done his doctorate in engineering in Munich he went to Göttingen where he received a doctor degree in philosophy. Until 1930 he worked at the Imperial University in Tokyo. In 1931 he was called to Aachen to fill the chair of mechanics. Later he also succeeded von Kármán as the director of the Aerodynamisches Institut. His research was closely related with his flight experience since he was a passionate pilot. He developed measurement techniques and instruments, and began to construct an intermittent operating supersonic wind tunnel. Prof. Wieselsberger deceased in 1941 at the age of 53 after a painful disease.
Between 1941 and 1944 the Aerodynamisches Institut strongly suffered from air raids and was finally relocated to Sonthofen in Bavaria. In 1947, after the collapse of the Third Reich, the Institute returned to Aachen. Immediately after the Second World War aerodynamics research was strictly forbidden in Germany. However, over the years the restrictions were abolished thanks to scientists like von Kármán.